| Analyte |
Phosphorylated |
Total |
| Akt Signaling |
|
|
| Akt (Ser473) |
P |
T |
| GSK-3α/β (Ser21/Ser9) |
P |
|
| Cell Cycle/Checkpoint Control |
|
|
| p53 (Ser15) |
P |
T |
| p53 (Ser37) |
P |
T |
| p53 (Ser46) |
P |
T |
| Chromatin Regulation/Acetylation |
|
|
| Histone H3 (Ser10) |
P |
|
| Immunology/Inflammation |
|
|
| IκB-α (Ser32/Ser36) |
P |
T |
| NF-κB p65 (Ser536) |
P |
|
| STAT2 (Tyr689) |
P |
|
| STAT3 (Ser727) |
P |
|
| STAT3 (Tyr705) |
P |
|
| STAT6 (Tyr641) |
P |
|
| Tyk2 (Tyr1054/Tyr1055) |
P |
|
| Glucose/Energy Metabolism |
|
|
| IGF-IR (Tyr1131) |
P |
|
| IR-β (Tyr1146) |
P |
|
| IRS-1 (Ser636/Ser639) |
P |
|
| MAP Kinase Signaling |
|
|
| ATF-2 (Thr71) |
P |
T |
| c-Jun (Ser63) |
P |
T |
| ERK1 (Thr202/Tyr204) |
P |
|
| ERK2 (Thr185/Tyr187) |
P |
T |
| ERK1/2 (Thr202/Tyr204, Thr185/Tyr187) |
P |
T |
| HSP27 (Ser78) |
P |
T |
| JNK (Thr183/Tyr185) |
P |
T |
| MEK1 (Ser217/Ser221) |
P |
T |
| p38 MAPK (Thr180/Tyr182) |
P |
T |
| p90RSK (Thr359/Ser363) |
P |
T |
| Neuroscience |
|
|
| CREB (Ser133) |
P |
T |
| TrkA (Tyr490) |
P |
|
| Translational Control |
|
|
| p70 S6 kinase (Thr421/Ser424) |
P |
|
| S6 ribosomal protein (Ser235/Ser236) |
P |
|
| Tyrosine Kinases |
|
|
| Bcr-Abl (Tyr245) |
P |
T |
| c-Abl (Tyr245) |
P |
|
| c-Abl (Tyr412) |
P |
|
| EGFR (Tyr) |
P |
|
| PDGF receptor-β (Tyr751) |
P |
|
| Src (Tyr416) |
P |
|
| MAPmates |
|
|
| Akt/PKB (Ser473) |
P |
T |
| Akt/PKB (Thr308) |
P |
T |
| ATF2 (Thr69/71) |
P |
T |
| BAD (Ser112) |
P |
T |
| Active Caspase 3 |
|
T |
| CREB (Ser133) |
P |
|
| EGF Receptor (pan Tyr) |
P |
T |
| Erb-B2/HER2 (pan Thr) |
P |
T |
| Erk/MAPK 1/2 (Thr185/Tyr187) |
P |
T |
| GAPDH |
|
T |
| H2A.X (Ser139) |
P |
|
| HSP27 (Ser78) |
P |
T |
| IGF1R (pan Tyr) |
P |
T |
| IκBα (Ser32) |
P |
T |
| IRS1 (pan Tyr) |
P |
T |
| JNK (Thr183/Tyr185) |
P |
T |
| c-Jun (Ser73) |
P |
|
| c-Kit (pan Tyr) |
P |
T |
| Lck (pan Tyr) |
P |
|
| MEK1 (Ser222) |
P |
T |
| c-Met/HGFR (pan Tyr) |
P |
T |
| MKK6 (Ser207/Thr211) |
P |
T |
| MSK1 (Ser212) |
P |
T |
| p21 |
|
T |
| p38 (Thr180/Tyr182) |
P |
T |
| p53 (Ser15) |
P |
T |
| p53 (Ser46) |
P |
T |
| p70 S6 Kinase (Thr412) |
P |
T |
| Cleaved PARP |
|
T |
| PDGF Receptor α (pan Tyr) |
P |
|
| PDGF Receptor β (pan Tyr, mouse) |
P |
|
| Rsk1 (Ser380) |
P |
|
| STAT1 (Tyr701) |
P |
T |
| STAT2 (Tyr690) |
P |
T |
| STAT3 (Ser727) |
P |
T |
| STAT3 (Tyr705) |
P |
T |
| STAT5A/B (Tyr694/699) |
P |
|
| STAT6 (Tyr641) |
P |
|
| ZAP-70 (pan Tyr) |
P |
|
| Multi-Pathway |
|
|
| CREB (Ser133) |
P |
|
| Erk/MAPK 1/2 (Thr185/Tyr187) |
P |
|
| IκBα (Ser32) |
P |
|
| JNK (Thr183/Tyr185) |
P |
|
| p38 (Thr180/Tyr182) |
P |
|
| p70 S6 Kinase (Thr412) |
P |
|
| STAT3 (Ser727) |
P |
|
| STAT5A/B (Tyr694/699) |
P |
|
| Human T Cell Receptor |
|
|
| CD3ε (pan Tyr) |
P |
|
| CREB (Ser133) |
P |
|
| Erk/MAPK 1/2 (Thr185/Tyr187) |
P |
|
| LAT (pan Tyr) |
P |
|
| Lck (pan Tyr) |
P |
|
| Syk (pan Tyr) |
P |
|
| ZAP-70 (pan Tyr) |
P |
|
| Human Apoptosis |
|
|
| Active Caspase 3 |
|
T |
| GAPDH |
|
T |
| Active Cleaved PARP |
|
T |
| Human MAPK/SAPK |
|
|
| ATF2 (Thr69/71) |
P |
|
| ERK/MAP Kinase 1/2 (Thr185/Tyr187) |
P |
|
| HSP27 (Ser78) |
P |
|
| JNK (Thr183/Tyr185) |
P |
|
| c-jun (Ser73) |
P |
|
| MEK1 (Ser222) |
P |
|
| MSK1 (Ser212) |
P |
|
| p38 (SAPK2A/B) (Thr180/Tyr182) |
P |
|
| p53 (Ser15) |
P |
|
| STAT1 (Tyr707) |
P |
|
| ATF2 (Thr69/71) |
P |
|
| ERK/MAP Kinase 1/2 (Thr185/Tyr187) |
P |
|
| Human Src Family Kinase |
|
|
| Blk (pan Tyr) |
P |
|
| Fgr (pan Tyr) |
P |
|
| Fyn (pan Tyr) |
P |
|
| Hck (pan Tyr) |
P |
|
| Lck (pan Tyr) |
P |
|
| Lyn (pan Tyr) |
P |
|
| Src (pan Tyr) |
P |
|
| Yes (pan Tyr) |
P |
|
| Phosphotyrosine Cell Signaling |
|
|
| Cbl (pY700/731/774) |
P |
|
| Crk (pY221/239) |
P |
|
| CUB domain containing protein 1 (pY734) |
P |
|
| EGFR (pY1110/1125) |
P |
|
| Ezrin (pY477) |
P |
|
| FAK (pY397/407) |
P |
|
| FAK (pY861) |
P |
|
| FRS2 (pY436) |
P |
|
| Fyb (pY697/651 (iso1/2)) |
P |
|
| Gab 1 (pY285/307/317) |
P |
|
| Gab 2 (pY266) |
P |
|
| Gab 2 (pY584) |
P |
|
| Growth hormone receptor (pY566) |
P |
|
| HER2 (pY1023) |
P |
|
| HGFR (met) (pY1003) |
P |
|
| Interleukin-15 receptor α chain (pY227) |
P |
|
| IRS1 (pY612) |
P |
|
| ITK (pY180) |
P |
|
| JAK3 (pY785) |
P |
|
| JNK1/2/3 (pY185/185/223) |
P |
|
| LAT (pY255) |
P |
|
| p38MAPKα (pY181) |
P |
|
| PDK1 (pY373/376) |
P |
|
| Pl3Kdp110d (pY485) |
P |
|
| Plakoglobin (γ-catenin) (pY548) |
P |
|
| PLCγ1 (pY1253) |
P |
|
| PLCγ2 (pY1197/1217) |
P |
|
| Raf 1 (pY340/341) |
P |
|
| RapGEF1 (GRF2) (pY504(522 in iso1)) |
P |
|
| SCF38 (pY20) |
P |
|
| SH2 domain containing protein 3A (pY231) |
P |
|
| SH2 domain containing protein 3A (pY95) |
P |
|
| Shc (pY349/350) |
P |
|
| SPTAN1 (pY1176) |
P |
|
| STAT3 (pY705) |
P |
|
| Tec (pY206) |
P |
|
| TfR (pY20) |
P |
|
| VEGFR1 (pY1169) |
P |
|
| WASP (pY291) |
P |
|
| ZAP70 (pY126) |
P |
|
